Clinical Trials
Hospital Henri Mondor, Creteil, France

Clinical Benefit of Using a Multifractional Er:YAG Laser Combined With a Spatially Modulated Ablative (SMA) Module for the Treatment of Striae Distensae: A Prospective Pilot Study in 20 Patients.

Lasers in Surgery and Medicine, 27 November 2018.

Jean Paul Meningaud, MD, PhD, Mounia SidAhmed-Mezi, PhD, Raphaelle Billon, MD, Kessara Rem, MD, Simone La Padula, MD, and Barbara Hersant, MD, PhD *

Background and Objective. Striae distensae (SD) are cutaneous lesions that often occur on the breasts, abdomen, hips, and thighs. The aim of this study is to evaluate the effectiveness of a new technique using a non-invasive Er:YAG laser combined with Spatially Modulated Ablation (SMA) module for the treatment of SD

Study Design/Materials and Methods. This prospective pilot clinical study included 20 patients with skin phototypes I to IV who are affected by SD. The Er:YAG 2940 nm laser with SMA module was used in scanning mode with fluences of 2.3 J/cm 2 , frequency of 3 Hz, and pulse duration of 0.3 milliseconds. The laser beam is split into several microspots and penetrates only by 50 mm in the epidermis thickness. This technology induces also the generation of acoustic waves to stimulate tissue regeneration. Each patient underwent six laser sessions. An objective and subjective assessment of SD were used. All adverse events were reported.

Results. Most patients reported good improvement and expressed their satisfaction with the treatment. Cutometric analysis showed significant improvement in skin elasticity at the end of study. Moreover, ultrasound analysis revealed an increase in dermal thickness (P < 0.01). POSAS scores decreased significantly at 3 and 6 months, reflecting improved skin quality. The average recovery time was 5 days, with no adverse effects reported.

Conclusions. Using Er:YAG laser (2,940nm) with SMA technology to treat SD resulted in improved volume and textural appearance without side effects. The elasticity and thickness of the dermis also improved. The Er:YAG laser with SMA module may be considered as a novel and effective technique to treat SD lesions with minimal time recovery.

* Department of Plastic, Reconstructive and Maxillo facial Surgery, Hopital Henri Mondor, Creteil 94010, France


Clinical Trials
Journal of Cosmetic Dermatology